RIE 2025 call for proposals: GlycoMechano, laureate project at IINS

Launched between January and April 2025, the University of Bordeaux’s third call for interdisciplinary and exploratory research (RIE) projects once again generated enthusiasm among the university’s scientific community. Sixty-seven eligible applications were submitted, once again mobilising all 11 research departments.

Following an evaluation process involving departmental management teams, an ad hoc committee from the Research Commission, an interdisciplinary group of young researchers, and previous winners, 20 proposals were approved by the University’s Executive Committee. Five of these proposals came from Bordeaux Neurocampus laboratories, including one from the IINS.

The two initial requirements have been retained for this edition: to propose an exploratory project – i.e. one that is original and breaks with past work – and to be rooted at the crossroads of scientific disciplines.

Find out more about the appeal and all the results

The GlycoMechano project

GlycoMechano – Cross-linking glycans to modulate the mechanical properties of the brain

Description:

The aim of the GlycoMechano project is to develop molecular tools capable of modulating the rigidity of the neural extracellular matrix (ECM) of neural tissue in order to study the effect of synaptic environment stiffening on plasticity.

Coordination:

• Morgane Rosendale, CNRS research fellow – Interdisciplinary Institute for Neurosciences (IINS, CNRS and University of Bordeaux unit)
  Bordeaux Neurocampus
• Frédéric Friscourt, – senior lecturer at the University of Bordeaux – Institut des sciences moléculaires (ISM, Bordeaux INP, CNRS and University of Bordeaux unit)
  Département Sciences de la matière et du rayonnement (SMR)