Synaptic pruning following NMDAR-dependent LTD preferentially affects isolated synapses
Camus Côme, Leval Léa, Viviana Villicana-Munoz, Jelinkova Sarka, Compans Benjamin, Gambino Frédéric, Herzog Etienne, Choquet Daniel, Hosy Eric
iScience. 2025-08-01
10.1016/j.isci.2025.113093

Secondary motor cortex tracks decision value during the learning of a non-instructed task
Elisabete Augusto, Vladimir Kouskoff, Nicolas Chenouard, Margaux Giraudet, Léa Peltier, Aron de Miranda, Alexy Louis, Lucille Alonso, Frédéric Gambino
Cell Reports. 2025-01-01
10.1016/j.celrep.2024.115152

Dynamic interplay between thalamic activity and Cajal-Retzius cells regulates the wiring of cortical layer 1
Ioana Genescu, Mar Aníbal-Martínez, Vladimir Kouskoff, Nicolas Chenouard, Caroline Mailhes-Hamon, Hugues Cartonnet, Ludmilla Lokmane, Filippo M. Rijli, Guillermina López-Bendito, Frédéric Gambino, Sonia Garel
Cell Reports. 2022-04-01
10.1016/j.celrep.2022.110667

Astroglial ER-mitochondria calcium transfer mediates endocannabinoid-dependent synaptic integration
Roman Serrat, Ana Covelo, Vladimir Kouskoff, Sebastien Delcasso, Andrea Ruiz-Calvo, Nicolas Chenouard, Carol Stella, Corinne Blancard, Benedicte Salin, Francisca Julio-Kalajzić, Astrid Cannich, Federico Massa, Marjorie Varilh, Severine Deforges, Laurie M. Robin, Diego De Stefani, Arnau Busquets-Garcia, Frederic Gambino, Anna Beyeler, Sandrine Pouvreau, Giovanni Marsicano
Cell Reports. 2021-12-01
10.1016/j.celrep.2021.110133

The integration of Gaussian noise by long-range amygdala inputs in frontal circuit promotes fear learning in mice
Mattia Aime, Elisabete Augusto, Vladimir Kouskoff, Tiago Campelo, Christelle Martin, Yann Humeau, Nicolas Chenouard, Frederic Gambino
eLife. 2020-11-30
10.7554/elife.62594

AMPAR-Dependent Synaptic Plasticity Initiates Cortical Remapping and Adaptive Behaviors during Sensory Experience
Tiago Campelo, Elisabete Augusto, Nicolas Chenouard, Aron de Miranda, Vladimir Kouskoff, Come Camus, Daniel Choquet, Frédéric Gambino
Cell Reports. 2020-09-01
10.1016/j.celrep.2020.108097

An increase in dendritic plateau potentials is associated with experience-dependent cortical map reorganization
Stéphane Pages, Nicolas Chenouard, Ronan Chéreau, Vladimir Kouskoff, Frédéric Gambino, Anthony Holtmaat
Preprint bioRxiv. 2020-07-14
10.1101/2020.07.13.200923

Eyes Wide Open on AMPAR Trafficking during Motor Learning
Frederic Gambino, Daniel Choquet
Neuron. 2020-03-01
10.1016/j.neuron.2020.02.006

Can NMDA Spikes Dictate Computations of Local Networks and Behavior?
Elisabete Augusto, Frédéric Gambino
Front. Mol. Neurosci.. 2019-09-27
10.3389/fnmol.2019.00238

Non-linear dendritic integration in frontal circuits shapes sensory discrimination in rodents
Mattia Aime, Elisabete Augusto, Vladimir Kouskoff, Christelle Martin, Yann Humeau, Nicolas Chenouard, Frédéric Gambino
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10.1101/569137

Sensory-evoked LTP driven by dendritic plateau potentials in vivo
Frédéric Gambino, Stéphane Pagès, Vassilis Kehayas, Daniela Baptista, Roberta Tatti, Alan Carleton, Anthony Holtmaat
Nature. 2014-08-31
10.1038/nature13664

The hippocampo-amygdala control of contextual fear expression is affected in a model of intellectual disability
Chun-Lei Zhang, Xander Houbaert, Marilyn Lepleux, Melissa Deshors, Elisabeth Normand, Frédéric Gambino, Etienne Herzog, Yann Humeau
Brain Struct Funct. 2014-08-27
10.1007/s00429-014-0882-x

Modality-specific thalamocortical inputs instruct the identity of postsynaptic L4 neurons
Gabrielle Pouchelon, Frédéric Gambino, Camilla Bellone, Ludovic Telley, Ilaria Vitali, Christian Lüscher, Anthony Holtmaat, Denis Jabaudon
Nature. 2014-05-14
10.1038/nature13390

Coronin 1 Regulates Cognition and Behavior through Modulation of cAMP/Protein Kinase A Signaling
Rajesh Jayachandran, Xiaolong Liu, Somdeb BoseDasgupta, Philipp Müller, Chun-Lei Zhang, Despina Moshous, Vera Studer, Jacques Schneider, Christel Genoud, Catherine Fossoud, Frédéric Gambino, Malik Khelfaoui, Christian Müller, Deborah Bartholdi, Helene Rossez, Michael Stiess, Xander Houbaert, Rolf Jaussi, Daniel Frey, Richard A. Kammerer, Xavier Deupi, Jean-Pierre de Villartay, Andreas Lüthi, Yann Humeau, Jean Pieters
PLoS Biol. 2014-03-25
10.1371/journal.pbio.1001820

The coincident activation of lemniscal and paralemniscal inputs can drive synaptic plasticity in layer 2/3 pyramidal neurons of the mouse somatosensory cortex in vivo
Kehayas Vassilis, Gambino Frédéric, Baptista Daniela, Pagès Stéphane, Holtmaat Anthony
Front. Syst. Neurosci.. 2014-01-01
10.3389/conf.fnsys.2014.05.00040

Lack of the presynaptic RhoGAP protein oligophrenin1 leads to cognitive disabilities through dysregulation of the cAMP/PKA signalling pathway
M. Khelfaoui, F. Gambino, X. Houbaert, B. Ragazzon, C. Muller, M. Carta, F. Lanore, B. N. Srikumar, P. Gastrein, M. Lepleux, C.-L. Zhang, M. Kneib, B. Poulain, S. Reibel-Foisset, N. Vitale, J. Chelly, P. Billuart, A. Luthi, Y. Humeau
Philosophical Transactions of the Royal Society B: Biological Sciences. 2013-12-02
10.1098/rstb.2013.0160

Target-specific vulnerability of excitatory synapses leads to deficits in associative memory in a model of intellectual disorder
X. Houbaert, C.-L. Zhang, F. Gambino, M. Lepleux, M. Deshors, E. Normand, F. Levet, M. Ramos, P. Billuart, J. Chelly, E. Herzog, Y. Humeau
Journal of Neuroscience. 2013-08-21
10.1523/JNEUROSCI.1457-13.2013

Spike-timing-dependent potentiation of sensory surround in the somatosensory cortex is facilitated by deprivation-mediated disinhibition
Frédéric Gambino, Anthony Holtmaat
Neuron. 2012-08-01
10.1016/j.neuron.2012.05.020

Synapses Let Loose for a Change: Inhibitory Synapse Pruning throughout Experience-Dependent Cortical Plasticity
Frédéric Gambino, Anthony Holtmaat
Neuron. 2012-04-01
10.1016/j.neuron.2012.04.005

In vivo evidence that TRAF4 is required for central nervous system myelin homeostasis
Sébastien Blaise, Marie Kneib, Adrien Rousseau, Frederic Gambino, Marie-Pierre Chenard, Nadia Messadeq, Martine Muckenstrum, Fabien Alpy, Catherine Tomasetto, Yann Humeau, Marie-Christine Rio
PLoS ONE. 2012-02-17
10.1371/journal.pone.0030917

Forebrain deletion of αGDI in adult mice worsens the pre-synaptic deficit at cortico-lateral amygdala synaptic connections
Veronica Bianchi, Frédéric Gambino, Luca Muzio, Daniela Toniolo, Yann Humeau, Patrizia D'Adamo
PLoS ONE. 2012-01-23
10.1371/journal.pone.0029763

Pre and Post Synaptic NMDA Effects Targeting Purkinje Cells in the Mouse Cerebellar Cortex
Etienne Lonchamp, Frédéric Gambino, Jean Luc Dupont, Frédéric Doussau, Antoine Valera, Bernard Poulain, Jean-Louis Bossu
PLoS ONE. 2012-01-19
10.1371/journal.pone.0030180

The coffin-lowry syndrome-associated protein RSK2 and neurosecretion
M. Zeniou-Meyer, F. Gambino, Mohamed-Raafet Ammar, Y. Humeau, N. Vitale
Cell Mol Neurobiol. 2010-11-01
10.1007/s10571-010-9578-9

Synaptic maturation at cortical projections to the lateral amygdala in a mouse model of rett syndrome
Frédéric Gambino, Malik Khelfaoui, Bernard Poulain, Thierry Bienvenu, Jamel Chelly, Yann Humeau
PLoS ONE. 2010-07-02
10.1371/journal.pone.0011399

IL1RAPL1 controls inhibitory networks during cerebellar development in mice
Frédéric Gambino, Marie Kneib, Alice Pavlowsky, Henriette Skala, Stéphane Heitz, Nicolas Vitale, Bernard Poulain, Malik Khelfaoui, Jamel Chelly, Pierre Billuart, Yann Humeau
European Journal of Neuroscience. 2009-10-01
10.1111/j.1460-9568.2009.06975.x

L-type voltage-dependent Ca2+ channels mediate expression of presynaptic LTP in amygdala
Elodie Fourcaudot, Frederic Gambino, Guillaume Casassus, Bernard Poulain, Yann Humeau, Andreas Lüthi
Nat Neurosci. 2009-08-02
10.1038/nn.2378

X-linked mental retardation: focus on synaptic function and plasticity
Yann Humeau, Frédéric Gambino, Jamel Chelly, Nicolas Vitale
Journal of Neurochemistry. 2009-04-01
10.1111/j.1471-4159.2009.05881.x

cAMP/PKA signaling and RIM1α mediate presynaptic LTP in the lateral amygdala
E. Fourcaudot, F. Gambino, Y. Humeau, G. Casassus, H. Shaban, B. Poulain, A. Luthi
Proceedings of the National Academy of Sciences. 2008-09-24
10.1073/pnas.0806938105

IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca2+-channel and neurite elongation
F. Gambino, A. Pavlowsky, A. Begle, J.-L. Dupont, N. Bahi, R. Courjaret, R. Gardette, H. Hadjkacem, H. Skala, B. Poulain, J. Chelly, N. Vitale, Y. Humeau
Proceedings of the National Academy of Sciences. 2007-05-14
10.1073/pnas.0701133104

IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca2+-channel and neurite elongation
F. Gambino, A. Pavlowsky, A. Begle, J.-L. Dupont, N. Bahi, R. Courjaret, R. Gardette, H. Hadjkacem, H. Skala, B. Poulain, J. Chelly, N. Vitale, Y. Humeau
Proceedings of the National Academy of Sciences. 2007-05-14
10.1073/pnas.0701133104